Poppers may lead to you losing consciousness and choking on your vomit.Users can also die from injury to red blood cells and reduced oxygen supply to vital organs, but this is very rare.Fatal ‘sudden sniffing death syndrome’ has been reported due to development of an abnormal heart rhythm when taking poppers.You shouldn’t take them if you have problems with your blood pressure, are on any blood pressure medication, or if you're taking erectile dysfunction medication such as Viagra. Sniffing poppers can make your blood pressure drop.

Sniffing poppers is potentially dangerous for anyone with heart problems, anaemia or glaucoma (an eye disease).